Glass is generally considered as a material with high chemical inertness due to its strong network structure. However, it is possible to lower this chemical inertness by continuously altering its structure especially in water.
On the other hand, glass has another interesting property, which retains metal as ions. Combination of this property and the above technology has enabled to create glass with low chemical inertness, which can also retain anti-microbial metal ions such as silver and copper. With the presence of water or moisture, the glass will release these metal ions gradually to function as anti-microbial material.
it is well known that these ion have antimicrobial effect. For example, silverware and copperware has been known to prevent decay of water and food since the ancient times.

• Freely design the anti-microbial effect and life span according to using purpose.
• Adaptable to all kind of resin in various grades.
• High performance at low concentration.
• Keep up transparency of resin such as PP, PC, ABS, AS.
• Adapt every molding and spinning as its heat-resistance is more than 500℃.
• Keep up high performance after washing and warm water environment.
• High level of safety.

With the presence of moisture, IONPURE releases a few Ag ions gradually. Ag ion has an ability to strongly bind to cellular enzyme of microbes and inhibit enzyme activity of cell wall, membrane, and nucleic acids. In a word, as microbes charged with minus on their surface, Ag ions that have plus are drawn toward microbes, and disturb their electric balance. so that microbes are burst their cell wall and extinguished.
Otherwise as Ag ions are taken into microbes, they react and bond to the cellular enzyme microbes. this inhibits enzyme activity and multiplication of microbes, thus extinguishing the microbes.

IONPURE can apply to the uses for compounding or coating or dipping of resin and fiber.

Sample	Number of cells		Log	Log (Blank)-Log (Samples)
	Beginning	18 hours later
PP fiber with 0.3% IONPURE	8×105	1×102	2.0	4.6
Blank	8×105	4×106	6.6	-

Sample	Number of cells		Log	Log (Blank)-Log (Samples)
	Beginning	18 hours later
PET fiber with 0.5% IONPURE	3×104	<1×102	<2.0	>5.0
Blank	3×104	1×107	7.0	-

Note 1) Bacteria used: Staphylococcus IFO 12732
Note 2)Test method: in accordance with JIS L 1902

Fiber containing Ionpure can keep up anti-microbial effect even after washing.

Heat-resistance of IONPURE is more than 500℃. as it is inorganic. It is possible to apply to every molding and spinning. Moreover, it can apply heat-resistant container made from resin.

IONPURE is not discolored by compounding and with age, as it is can control the speed of releasing metal ions which have anti-microbial effect.

To be enable to design freely it's life span of effect by combining glass composition and metal ions having anti-microbial effect is only IONPURE.

Sample PP fiber	Number of cells		Log	Log (Black)-Log (Samples)
	Beginning	24 hours later
Boiled 500 hours	1×105	1×104	4	3
Boiled 1000 hours	1×105	3×104	4.4	2.6
Blank	1×105	1×107	7.0	-

Note 1) Used bacteria: Escherichia coli NBRC 3972
Note 2) Test method: in accordance with JIS Z 2801

Sample	Number of cells		Log	Log (Blank)-Log (Samples)
	Beginning	24 hours later
GP-PS with 0.15% IONPURE	2×105	<1×102	<2.0	>5.0
Blank	2×105	1×107	7.0	-

Note 1)Bacteria used: Escherichia coli NBRC 3972
Note 2)Test method: in accordance with JIS Z 2801

IONPURE does not effect the properties of plastics.

Strength test	Test method		Material
			Blank PC plate	PC plate with 0.5% IONPURE
Tensile strength 50mm/min	ASTM D-638 (kg/cm2)	At yield point	642	639
		At break point	746	662
Bending strength 3mm/min	ASTM D-790(kg/cm2)		924	931
Impact strength	ASTM D-256(kg・cm/cm2)		82.60	83.86
Heat transforming temperature load 18.5kg	ASTM D-648 (℃)		132.4	132.8

IONPURE has acquired various safety data for each grade of the product. Following are examples of safety data.

• Acute oral toxicity
  There was no case of abnormal reaction or death by single oral administration of 5000mg/kg(2000mg/kg) of IONPURE to mice.
• Primary skin irritation
  No skin irritation response was observed an albino rabbits during or after the skin irritation test suggested in the OECD Chemical Substance Toxicity Test Guidance.(1981)
• Mutagenicity
  The mutagenicity test based on the bulletin No.77 of the Labor Ministry of Japan (1st Sep.1989)resulted in no increase in reverse mutation and mutagenicity was confirmed to be negative.
• Skin sensitization
  The skin sensitization test using maximization method demonstrated no skin sensitization on guinea pigs.
• Inhibition of colony forming
  In accordance with "Guidelines for Biological Tests of Medical Devices" (No.99), the value was 0.51mg/ml for inhibition of 50% colony forming (IC50).

In addition to above test results, eye irritancy test, photo toxicity test, and repeat insult patch test have been performed for other grades of IONPURE. Also, other products containing IONPURE have exhibited excellent safety data in human patch test and quality assurance test for food containers and appliances based on Food Hygiene Law of Japan.